He's just talking about seeing his face in the tabloids, he wasn't the first celebrity to talk about it in a song and certainly not the last.
The next part of the line is :
"when a nigga's gettin richer
They come to get ya"
and that makes this pretty clear. As we all know, generally speaking fame = money. Hence the phrase "Fortune & Fame", as Tupac also sang about in the song "Fame". The two go hand in hand - that's generally understood as fact.
So to break it down in the most simple terms, Tupac is talking about people coming to get him, as in bring him down or hurt his character, because they see his face in every newspaper and therefore realize that he has money.
This is what happens to everyone famous. You have money, people try and take what they can get. Let's look at Michael Jackson as the ultimate example. Do you know how many bogus lawsuits are filed against Michael every year? Hundreds of them. They're all complete and utter nonsense. You hear reports of people that have never met him suing him for psychological damages because they convinced themselves that he was secretly in love with them despite never having met them. Then they get stalkerish and get rebuffed by security and try and sue. There's a guy trying to sue now, claiming that the O2 concerts violate an agreement he had with Michael for a Jackson 5 reunion tour. There's no way in hell Michael would ever do that, he has rebuffed much bigger sums of money and is completely anti- the idea of touring with his brothers. Yet this sycophantic asshole promoter guy somewhere has convinced himself that he's right, and that he isn't just a delusional douchebag. There are so many examples of this!
Happens to everyone in these circumstances. If you're a celebrity and you've obviously got money it's something you have to deal with. People will come to get you. Whether it's journalists with an axe to grind, stalkers, groupies, delusional people, or in some cases, just people from the street life you used to live before you made it.